A prospective, active haemovigilance study with combined cohort analysis of 19 175 transfusions of platelet components prepared with amotosalen–<scp>UVA</scp> photochemical treatment

Knutson, Folke; Claude Osselaer, Jean; Pierelli, Luca; Lozano, Miquel; Cid, Joan; Tardivel, R.; Garraud, Olivier; Hervig, Tor; Domanović, Dragoslav; Cukjati, Marko; Gudmundson, S.; Björg Hjálmarsdóttir, Ína; Castrillo, Azucena; González, R.; Brihante, D.; Santos, Marlene; Schlenke, Peter; Elliott, Anne; Js, Lin; Tappe, David; Stassinopoulos, Adonis; Green, J.; Corash, Laurence

doi:10.1111/vox.12287

Public

A prospective, active haemovigilance study with combined cohort analysis of 19 175 transfusions of platelet components prepared with amotosalen–UVA photochemical treatment

Published in Vox Sanguinis • May 15, 2015

Authors:

Folke Knutson

Jean Claude Osselaer

Luca Pierelli

Abstract

BACKGROUND AND OBJECTIVES: A photochemical treatment process (PCT) utilizing amotosalen and UVA light (INTERCEPT(™) Blood System) has been developed for inactivation of viruses, bacteria, parasites and leucocytes that can contaminate blood components intended for transfusion. The objective of this s...

Subject

Medicine

Plateletpheresis

Adverse effect

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