Oligo Safety Working Group Exaggerated Pharmacology Subcommittee Consensus Document

Kornbrust, Doug; Cavagnaro, Joy; A. Levin, Arthur; W.-D. Foy, Jeffrey; A Pavco, P; Gamba‐Vitalo, Christina; Guimond, Alain

doi:10.1089/nat.2012.0399

Public

Oligo Safety Working Group Exaggerated Pharmacology Subcommittee Consensus Document

Published in Nucleic Acid Therapeutics • Jan 4, 2013

Authors:

Doug Kornbrust

Joy Cavagnaro

Arthur A. Levin

Abstract

This document summarizes the current consensus opinion of the Exaggerated Pharmacology (EP) Subcommittee of the Oligonucleotide Safety Working Group on the appropriate strategies to assess potential adverse effects caused by an "exaggerated" degree of the intended pharmacologic activity of an oligon...

Subject

Pharmacology

Medicine

Psychology

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