Antibody‐functionalized nanoparticles for imaging cancer: influence of conjugation to gold nanoparticles on the biodistribution of <sup>89</sup>Zr‐labeled cetuximab in mice

Karmani, Linda; Labar, Daniel; Valembois, Vanessa; Bouchat, V.; Ganesh Nagaswaran, Praveen; Bol, Anne; Gillart, J.; Levêque, Philippe; Bouzin, Caroline; Bonifazi, Davide; Michiels, Carine; Féron, Olivier; Grégoire, Vincent; Lucas, Stéphane; Vander Borght, Thierry; Gallez, Bernard

doi:10.1002/cmmi.1539

Public

Antibody‐functionalized nanoparticles for imaging cancer: influence of conjugation to gold nanoparticles on the biodistribution of 89Zr‐labeled cetuximab in mice

Published in Contrast Media & Molecular Imaging • Jun 6, 2013

Authors:

Linda Karmani

Daniel Labar

Vanessa Valembois

Abstract

Antibody-labeled gold nanoparticles represent a promising novel tool regarding cancer imaging and therapy. Nevertheless, the characterization of biodistribution of such immunonanocarriers has been poorly documented. In this study, the biodistribution of (89)Zr-labeled cetuximab before and after the ...

Subject

Cetuximab

Biodistribution

In vivo

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