Human IL-10 is a chemoattractant for CD8+ T lymphocytes and an inhibitor of IL-8-induced CD4+ T lymphocyte migration.

Jinquan, T; G Larsen, C; Gesser, Borbala; Matsushima, Koji; Thestrup‐Pedersen, Kristian

doi:10.4049/jimmunol.151.9.4545

Public

Human IL-10 is a chemoattractant for CD8+ T lymphocytes and an inhibitor of IL-8-induced CD4+ T lymphocyte migration.

Published in The Journal of Immunology • Nov 1, 1993

Authors:

T Jinquan

C G Larsen

Borbala Gesser

Abstract

Human IL-10 (hIL-10) is a newly described cytokine that was originally identified as a cytokine synthesis inhibitory factor regulating the production of several pro-inflammatory cytokines such as IL-1 alpha, IL-1 beta, IL-6, IL-8, TNF-alpha, and IFN-gamma. Additionally, hIL-10 also inhibits the macr...

Subject

Chemotaxis

T lymphocyte

Immunology

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