Inhibition of human cytotoxic T lymphocyte activity in vitro by autologous peripheral blood granulocytes.

Peripheral blood granulocytes from normal healthy donors were found to reproducibly inhibit the cytolytic effector function of specifically sensitized cytotoxic T lymphocytes in vitro when co-incubated with these effector cells and target cells in 8 hr 51Cr release assays. Inhibition required intact... View More