Hydrogel Spacer Prospective Multicenter Randomized Controlled Pivotal Trial: Dosimetric and Clinical Effects of Perirectal Spacer Application in Men Undergoing Prostate Image Guided Intensity Modulated Radiation Therapy

Mariados, Neil; Sylvester, John; Shah, Dhiren; I. Karsh, Lawrence; Hudes, Richard; Beyer, David; Kurtzman, Steven; A. Bogart, Jeffrey; Hsi, R.A.; Kos, Michael; J. Ellis, Rodney; D. Logsdon, Mark; Zimberg, S.H.; Forsythe, Kevin; Zhang, Hong; Soffen, Edward; Francke, Patrick; Mantz, C.A.; J. Rossi, Peter; L. DeWeese, Theodore; A. Hamstra, Daniel; Bosch, Walter; A. Gay, Hiram; M. Michalski, Jeff

doi:10.1016/j.ijrobp.2015.04.030

Public

Hydrogel Spacer Prospective Multicenter Randomized Controlled Pivotal Trial: Dosimetric and Clinical Effects of Perirectal Spacer Application in Men Undergoing Prostate Image Guided Intensity Modulated Radiation Therapy

Published in International Journal of Radiation Oncology*Biology*Physics • Apr 23, 2015

Authors:

Neil Mariados

John Sylvester

Dhiren Shah

Abstract

PURPOSE: Perirectal spacing, whereby biomaterials are placed between the prostate and rectum, shows promise in reducing rectal dose during prostate cancer radiation therapy. A prospective multicenter randomized controlled pivotal trial was performed to assess outcomes following absorbable spacer (Sp...

Subject

Medicine

Prostate cancer

Randomized controlled trial

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