Human glutathione S-transferase theta (GSTT1): cDNA cloning and the characterization of a genetic polymorphism

Pemble, Sally; Schroeder, Karsten; R Spencer, S; J. Meyer, David; Hallier, Ernst; M. Bolt, Hermann; Ketterer, B; B Taylor, J

doi:10.1042/bj3000271

Public

Human glutathione S-transferase theta (GSTT1): cDNA cloning and the characterization of a genetic polymorphism

Published in Biochemical Journal • May 15, 1994

Authors:

Sally Pemble

Karsten Schroeder

S R Spencer

Abstract

In humans, glutathione-dependent conjugation of halomethanes is polymorphic, with 60% of the population classed as conjugators and 40% as non-conjugators. We report the characterization of the genetic polymorphism causing the phenotypic difference. We have isolated a cDNA that encodes a human class ...

Subject

Glutathione

Complementary DNA

Biology

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