The ER chaperone GRP78 is associated with the severity of cerulein-induced pancreatic inflammation via regulating apoptosis of pancreatic acinar cells.

Y, Liu; ZG, Zhou; KL, Chen; B, Zhou; L, Yang; H, Yan; Y, Li

doi:10.5754/hge12281

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The ER chaperone GRP78 is associated with the severity of cerulein-induced pancreatic inflammation via regulating apoptosis of pancreatic acinar cells.

Shared by NobleBlocks on Sep 1, 2012 • 12:00 AM UTC

Authors:

Liu Y

Zhou ZG

Chen KL

Abstract

Background/aims To study the potential role of the 78kDa glucose regulated protein (GRP78) in the pathogenesis of acute pancreatitis (AP) in vitro.Methodology AR42J cells were stimulated by cerulein or cerulein plus lipoplysaccharide (LPS). The severity of pancreatic inflammation was evaluated by am...

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