Hyperfractionated Radiation Therapy With or Without Concurrent Low-Dose Daily Cisplatin in Locally Advanced Squamous Cell Carcinoma of the Head and Neck: A Prospective Randomized Trial

Jeremić, Branislav; Shibamoto, Yuta; Miličić, Biljana; Nikolic, Nebojsa; Dagović, Aleksandar; Aleksandrovic, Jasna; Vaskovic, Zeljko; Tadić, Ljiljana

doi:10.1200/jco.2000.18.7.1458

Public

Hyperfractionated Radiation Therapy With or Without Concurrent Low-Dose Daily Cisplatin in Locally Advanced Squamous Cell Carcinoma of the Head and Neck: A Prospective Randomized Trial

Published in Journal of Clinical Oncology • Apr 7, 2000

Authors:

Branislav Jeremić

Yuta Shibamoto

Biljana Miličić

Abstract

PURPOSE: To investigate whether the addition of cisplatin (CDDP) to hyperfractionation (Hfx) radiation therapy (RT) offers an advantage over the same Hfx RT given alone in locally advanced (stages III and IV) squamous cell carcinoma of the head and neck. PATIENTS AND METHODS: One hundred thirty pati...

Subject

Medicine

Hyperfractionation

Radiation therapy

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