MicroRNA profiles in hippocampal granule cells and plasma of rats with pilocarpine-induced epilepsy – comparison with human epileptic samples

Roncon, Paolo; Soukupovà, Marie; Binaschi, Anna; Falcicchia, Chiara; Zucchini, Silvia; Ferracin, Manuela; R. Langley, Sarah; Petretto, Enrico; R. Johnson, Michael; Marucci, Gianluca; Michelucci, Roberto; Rubboli, Guido; Simonato, Michele

doi:10.1038/srep14143

Public

MicroRNA profiles in hippocampal granule cells and plasma of rats with pilocarpine-induced epilepsy – comparison with human epileptic samples

Published in Scientific Reports • Sep 18, 2015

Authors:

Paolo Roncon

Marie Soukupovà

Anna Binaschi

Abstract

The identification of biomarkers of the transformation of normal to epileptic tissue would help to stratify patients at risk of epilepsy following brain injury, and inform new treatment strategies. MicroRNAs (miRNAs) are an attractive option in this direction. In this study, miRNA microarrays were p...

Subject

Epilepsy

Pilocarpine

Hippocampal formation

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