Increased level of H19 long noncoding RNA promotes invasion, angiogenesis, and stemness of glioblastoma cells

Jiang, Xiaochun; Yan, Yukui; Hu, Minghua; Chen, Xiande; Wang, Yaxian; Dai, Yi; Wu, Degang; Wang, Yongsheng; Zhuang, Zhixiang; Xia, Hongping

doi:10.3171/2014.12.jns1426

Public

Increased level of H19 long noncoding RNA promotes invasion, angiogenesis, and stemness of glioblastoma cells

Published in Journal of neurosurgery • Aug 14, 2015

Authors:

Xiaochun Jiang

Yukui Yan

Minghua Hu

Abstract

OBJECT Increased levels of H19 long noncoding RNA (lncRNA) have been observed in many cancers, suggesting that overexpression of H19 may be important in the development of carcinogenesis. However, the role of H19 in human glioblastoma is still unclear. The object of this study was to examine the lev...

Subject

Angiogenesis

Carcinogenesis

Cancer research

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