Equivalence of Three or Four Cycles of Bleomycin, Etoposide, and Cisplatin Chemotherapy and of a 3- or 5-Day Schedule in Good-Prognosis Germ Cell Cancer: A Randomized Study of the European Organization for Research and Treatment of Cancer Genitourinary Tract Cancer Cooperative Group and the Medical Research Council

de Wit, Ronald; Roberts, J.T.; M Wilkinson, P; de Mulder, P.H.M.; M. Mead, Graham; D. Fosså, Sophie; Cook, Pat; de Prijck, Linda; Stenning, Sally; Collette, Laurence

doi:10.1200/jco.2001.19.6.1629

Public

Equivalence of Three or Four Cycles of Bleomycin, Etoposide, and Cisplatin Chemotherapy and of a 3- or 5-Day Schedule in Good-Prognosis Germ Cell Cancer: A Randomized Study of the European Organization for Research and Treatment of Cancer Genitourinary Tract Cancer Cooperative Group and the Medical Research Council

Published in Journal of Clinical Oncology • Mar 15, 2001

Authors:

Ronald de Wit

J.T. Roberts

P M Wilkinson

Abstract

PURPOSE: To test the equivalence of three versus four cycles of bleomycin, etoposide, and cisplatin (BEP) and of the 5-day schedule versus 3 days per cycle in good-prognosis germ cell cancer. PATIENTS AND METHODS: The study was designed as a 2 x 2 factorial trial. The aim was to rule out a 5% decrea...

Subject

Etoposide

Medicine

Germ cell tumors

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