Cannabinoid actions at TRPV channels: effects on TRPV3 and TRPV4 and their potential relevance to gastrointestinal inflammation

De Petrocellis, L.; Orlando, P.; Schiano Moriello, A.; Aviello, G.; Stott, C.; A. Izzo, A.; Di Marzo, V.

doi:10.1111/j.1748-1716.2011.02338.x

Public

Cannabinoid actions at TRPV channels: effects on TRPV3 and TRPV4 and their potential relevance to gastrointestinal inflammation

Shared by NobleBlocks on Aug 12, 2011 • 12:00 AM UTC

Authors:

L. De Petrocellis

P. Orlando

A. Schiano Moriello

Abstract

Abstract Aim: Plant cannabinoids, like Δ 9 ‐tetrahydrocannabinol (THC) and cannabidiol (CBD), activate/desensitize thermosensitive transient receptor potential (TRP) channels of vanilloid type‐1 or ‐2 (TRPV1 or TRPV2). We investigated whether cannabinoids also activate/desensitize two other ‘thermo‐...

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