The human transcriptome across tissues and individuals

Melé, Marta; G. Ferreira, Pedro; Reverter, Ferrán; S. DeLuca, David; Monlong, Jean; Sammeth, Michael; Young, Taylor; M. Goldmann, Jakob; D. Pervouchine, Dmitri; J. Sullivan, Timothy; Johnson, Rory; V. Segrè, Ayellet; Djebali, Sarah; Niarchou, Anastasia; A. Wright, Fred; Lappalainen, Tuuli; Calvo, Miquel; Getz, Gad; T. Dermitzakis, Emmanouil; Ardlie, Kristin; Guigó, Roderic

doi:10.1126/science.aaa0355

Public

The human transcriptome across tissues and individuals

Published in Science • May 7, 2015

Authors:

Marta Melé

Pedro G. Ferreira

Ferrán Reverter

Abstract

Transcriptional regulation and posttranscriptional processing underlie many cellular and organismal phenotypes. We used RNA sequence data generated by Genotype-Tissue Expression (GTEx) project to investigate the patterns of transcriptome variation across individuals and tissues. Tissues exhibit char...

Subject

Biology

Genetic variation

Transcriptome

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