Randomized trial of intensive cyclophosphamide, epirubicin, and fluorouracil chemotherapy compared with cyclophosphamide, methotrexate, and fluorouracil in premenopausal women with node-positive breast cancer. National Cancer Institute of Canada Clinical Trials Group.

N. Levine, Mark; Bramwell, V.; I. Pritchard, Kathleen; Norris, B.; E. Shepherd, Lois; Abu-Zahra, Hakam; Findlay, B.; Warr, David; M. J. S. Bowman, David; D. Myles, James; Arnold, Andrew; Vandenberg, Ted; G. MacKenzie, Robert; Robert, J; Ottaway, J.; J. Burnell, Margot; Kwesi O. Williams, Christopher; Tu, Dan‐Na

doi:10.1200/jco.1998.16.8.2651

Public

Randomized trial of intensive cyclophosphamide, epirubicin, and fluorouracil chemotherapy compared with cyclophosphamide, methotrexate, and fluorouracil in premenopausal women with node-positive breast cancer. National Cancer Institute of Canada Clinical Trials Group.

Published in Journal of Clinical Oncology • Aug 1, 1998

Authors:

Mark N. Levine

V. Bramwell

Kathleen I. Pritchard

Abstract

PURPOSE: To determine the relative efficacy of an intensive cyclophosphamide, epirubicin, and fluorouracil (CEF) adjuvant chemotherapy regimen compared with cyclophosphamide, methotrexate, and fluorouracil (CMF) in node-positive breast cancer. PATIENTS AND METHODS: Premenopausal women with node-posi...

Subject

Medicine

Epirubicin

Fluorouracil

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