Risk of fatal and nonfatal lactic acidosis with metformin use in type 2 diabetes mellitus

R. Salpeter, Shelley; Greyber, Elizabeth; A Pasternak, Gary; E. Salpeter, E.

doi:10.1002/14651858.cd002967.pub4

Public

Risk of fatal and nonfatal lactic acidosis with metformin use in type 2 diabetes mellitus

Published in Cochrane Database of Systematic Reviews • Apr 13, 2010

Authors:

Shelley R. Salpeter

Elizabeth Greyber

Gary A Pasternak

Abstract

BACKGROUND: Metformin is an oral anti-hyperglycemic agent that has been shown to reduce total mortality compared to other anti-hyperglycemic agents, in the treatment of type 2 diabetes mellitus. Metformin, however, is thought to increase the risk of lactic acidosis, and has been considered to be con...

Subject

Metformin

Medicine

Lactic acidosis

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