Genomic analysis of diversity, population structure, virulence, and antimicrobial resistance in <i>Klebsiella pneumoniae</i> , an urgent threat to public health

E. Holt, Kathryn; Wertheim, Heiman; N. Zadoks, Ruth; Baker, Stephen; A. Whitehouse, Chris; A. B. Dance, David; Jenney, Adam; R. Connor, Thomas; Yang Hsu, Li; A. Severin, Juliëtte; Brisse, Sylvain; Cao, Hanwei; J. Wilksch, Jonathan; L. Gorrie, Claire; B. Schultz, Mark; Edwards, David; Van Nguyen, Kinh; Vu Nguyen, Trung; Tuyet Dao, Trinh; Mensink, Martijn; Le Minh, Vien; Thi Khanh Nhu, Nguyen; Schultsz, Constance; Kuntaman, Kuntaman; N. Newton, Paul; E. Moore, Catrin; A. Strugnell, Richard; R. Thomson, Nicholas

doi:10.1073/pnas.1501049112

Public

Genomic analysis of diversity, population structure, virulence, and antimicrobial resistance in Klebsiella pneumoniae , an urgent threat to public health

Published in Proceedings of the National Academy of Sciences • Jun 22, 2015

Authors:

Kathryn E. Holt

Heiman Wertheim

Ruth N. Zadoks

Abstract

Klebsiella pneumoniae is now recognized as an urgent threat to human health because of the emergence of multidrug-resistant strains associated with hospital outbreaks and hypervirulent strains associated with severe community-acquired infections. K. pneumoniae is ubiquitous in the environment and ca...

Subject

Klebsiella pneumoniae

Virulence

Antibiotic resistance

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