Differences in survival-promoting effects and intracellular signaling properties of BDNF and IGF-1 in cultured cerebral cortical neurons.

M, Yamada; K, Tanabe; K, Wada; K, Shimoke; Y, Ishikawa; T, Ikeuchi; S, Koizumi; H, Hatanaka

doi:10.1046/j.1471-4159.2001.00497.x

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Differences in survival-promoting effects and intracellular signaling properties of BDNF and IGF-1 in cultured cerebral cortical neurons.

Shared by NobleBlocks on Sep 1, 2001 • 12:00 AM UTC

Authors:

Yamada M

Tanabe K

Wada K

Abstract

Brain-derived neurotrophic factor (BDNF) and insulin-like growth factor-1 (IGF-1) act on various neurons of the CNS as neurotrophic factors promoting neuronal differentiation and survival. We examined the survival-promoting effects of BDNF and IGF-1 on serum deprivation-induced death in cultured cer...

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