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Cancer stem cells in glioblastoma.

Published in Genes & development • Jun 15, 2015
Authors:
Justin D Lathia
,
Stephen C Mack
,
Erin E Mulkearns-Hubert

Abstract

Tissues with defined cellular hierarchies in development and homeostasis give rise to tumors with cellular hierarchies, suggesting that tumors recapitulate specific tissues and mimic their origins. Glioblastoma (GBM) is the most prevalent and malignant primary brain tumor and contains self-renewing,...

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