Are the PE‐PGRS proteins of <i>Mycobacterium tuberculosis</i> variable surface antigens?

Banu, Sayera; Honoré, Nadine; Saint‐Joanis, Brigitte; J. Philpott, Dana; Prévost, Marie‐Christine; T. Cole, Stewart

doi:10.1046/j.1365-2958.2002.02813.x

Public

Are the PE‐PGRS proteins of Mycobacterium tuberculosis variable surface antigens?

Published in Molecular Microbiology • Apr 1, 2002

Authors:

Sayera Banu

Nadine Honoré

Brigitte Saint‐Joanis

Abstract

Mycobacterium tuberculosis H37Rv contains 67 PE-PGRS genes, with multiple tandem repetitive sequences, encoding closely related proteins that are exceptionally rich in glycine and alanine. As no functional information was available, 10 of these genes were selected and shown to be expressed in vitro ...

Subject

Biology

Mycobacterium tuberculosis

Antigen

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