Non‐genetic risk factors and the development of inhibitors in haemophilia: a comprehensive review and consensus report

Astermark, Jan; Altisent, Carmen; Bátorová, Angelika; João Diniz, Maria; Gringeri, A.; André Holme, Pål; Karafoulidou, Anastasia; F. LOPEZ‐FERNÁNDEZ, M.; M. Reipert, Birgit; Rocino, Angiola; Schiavoni, M.; von Depka, Mario; Windyga, Jerzy; Fijnvandraat, Karin; BEHALF OF THE EUROPEAN HAEMOPHILIA THERAPY STANDARDISATION BOARD (EHTSB), ON

doi:10.1111/j.1365-2516.2010.02231.x

Public

Non‐genetic risk factors and the development of inhibitors in haemophilia: a comprehensive review and consensus report

Published in Haemophilia • Apr 14, 2010

Authors:

Jan Astermark

Carmen Altisent

Angelika Bátorová

Abstract

SUMMARY: The development of inhibitors to the infused factor in patients with haemophilia is a serious clinical problem. Recent evidence suggests that alongside the strong genetic contribution to inhibitor formation, there are a number of non-genetic factors--perceived by the immune system as danger...

Subject

Haemophilia

Medicine

Haemophilia A

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