Galectin-9 Induces Maturation of Human Monocyte-Derived Dendritic Cells

Dai, Shu-Yan; Nakagawa, Ryusuke; Itoh, Aiko; Murakami, Hiromoto; Kashio, Yumiko; Abe, Hiroko; Katoh, Shigeki; Kontani, Keiichi; Kihara, Minoru; Zhang, Shulan; Hata, Toshiyuki; Nakamura, Takanori; Yamauchi, Akira; Hirashima, Mitsuomi

doi:10.4049/jimmunol.175.5.2974

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Galectin-9 Induces Maturation of Human Monocyte-Derived Dendritic Cells

Published in The Journal of Immunology • Sep 1, 2005

Authors:

Shu-Yan Dai

Ryusuke Nakagawa

Aiko Itoh

Abstract

Maturation of dendritic cells (DCs) is critical for initiation of immune responses and is regulated by various stimulatory signals. We assessed the role of galectin (Gal)-9 in DC maturation. Culture of immature DCs with exogenous Gal-9 markedly increased the surface expression of CD40, CD54, CD80, C...

Subject

CD80

Cell biology

Galectin

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