Tau and Aβ42 in Cerebrospinal Fluid from Healthy Adults 21–93 Years of Age: Establishment of Reference Values

Sjögren, Magnus; Vanderstichele, Hugo; Ågren, Hans; Zachrisson, Olof; Edsbagge, Mikael; Wikkelsø, Carsten; Skoog, Ingmar; Wallin, Anders; Wahlund, Lars‐Olof; Marcusson, Jan; Nägga, Katarina; Andreasen, Niels; Davidsson, Pia; Vanmechelen, Eugeen; Blennow, Kaj

doi:10.1093/clinchem/47.10.1776

Public

Tau and Aβ42 in Cerebrospinal Fluid from Healthy Adults 21–93 Years of Age: Establishment of Reference Values

Published in Clinical Chemistry • Oct 1, 2001

Authors:

Magnus Sjögren

Hugo Vanderstichele

Hans Ågren

Abstract

BACKGROUND: Tau protein and the 42-amino acid form of beta-amyloid (Abeta42) measured in cerebrospinal fluid (CSF) have been proposed as potential biochemical diagnostic markers for Alzheimer disease. For the introduction of these assays in clinical practice, adequate reference values are of importa...

Subject

Cerebrospinal fluid

Medicine

Internal medicine

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