Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in Caenorhabditis elegans

S. Kamath, Ravi; Martinez-Campos, Maruxa; Zipperlen, Peder; Fraser, Andrew; Ahringer, Julie

doi:10.1186/gb-2000-2-1-research0002

Public

Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in Caenorhabditis elegans

Published in Genome biology • Dec 20, 2000

Authors:

Ravi S. Kamath

Maruxa Martinez-Campos

Peder Zipperlen

Abstract

BACKGROUND: In Caenorhabditis elegans, injection of double-stranded RNA (dsRNA) results in the specific inactivation of genes containing homologous sequences, a technique termed RNA-mediated interference (RNAi). It has previously been shown that RNAi can also be achieved by feeding worms Escherichia...

Subject

RNA interference

Biology

Caenorhabditis elegans

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!