Short Hairpin RNA (shRNA): Design, Delivery, and Assessment of Gene Knockdown

J. Taxman, Debra; B. Moore, Chris; H. Guthrie, Elizabeth; Tze-Han Huang, Max

doi:10.1007/978-1-60761-657-3_10

Public

Short Hairpin RNA (shRNA): Design, Delivery, and Assessment of Gene Knockdown

Published in Methods in molecular biology • Jan 1, 2010

Authors:

Debra J. Taxman

Chris B. Moore

Elizabeth H. Guthrie

Abstract

Shortly after the cellular mechanism of RNA interference (RNAi) was first described, scientists began using this powerful technique to study gene function. This included designing better methods for the successful delivery of small interfering RNAs (siRNAs) and short hairpin RNAs (shRNAs) into mamma...

Subject

Small hairpin RNA

Gene knockdown

RNA interference

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