Depletion of definitive gut endoderm in<i>Sox17</i>-null mutant mice

Kanai-Azuma, Masami; Kanai, Yoshiakira; M. Gad, Jacqueline; Tajima, Youichi; Taya, Choji; Kurohmaru, Masamichi; Sanai, Yutaka; Yonekawa, Hiromichi; Yazaki, Kazumori; P. L. Tam, Patrick; Hayashi, Yoshihiro

doi:10.1242/dev.129.10.2367

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Depletion of definitive gut endoderm inSox17-null mutant mice

Shared by NobleBlocks on May 15, 2002 • 12:00 AM UTC

Authors:

Masami Kanai-Azuma

Yoshiakira Kanai

Jacqueline M. Gad

Abstract

In the mouse, the definitive endoderm is derived from the epiblast during gastrulation, and, at the early organogenesis stage, forms the primitive gut tube, which gives rise to the digestive tract, liver, pancreas and associated visceral organs. The transcription factors, Sox17 (a Sry-related HMG bo...

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