High levels of interleukin-8 in the blood and alveolar spaces of patients with pneumonia and adult respiratory distress syndrome

Chollet‐Martin, Sylvie; Montravers, Philippe; Gibert, Claude; Elbim, Carole; M. Desmonts, J.; Fagon, Jean-Yves; A Gougerot-Pocidalo, M

doi:10.1128/iai.61.11.4553-4559.1993

Public

High levels of interleukin-8 in the blood and alveolar spaces of patients with pneumonia and adult respiratory distress syndrome

Published in Infection and Immunity • Nov 1, 1993

Authors:

Sylvie Chollet‐Martin

Philippe Montravers

Claude Gibert

Abstract

There is ample experimental evidence that polymorphonuclear neutrophils (PMN) play a critical role in the pathogenesis of the adult respiratory distress syndrome (ARDS). Since interleukin-8 (IL-8) is a strong chemotactic factor for PMN, we measured IL-8 levels in plasma and bronchoalveolar lavage (B...

Subject

ARDS

Bronchoalveolar lavage

Pathogenesis

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