Estimation of the number of nucleotide substitutions when there are strong transition-transversion and G+C-content biases.

Tamura, Koichiro

doi:10.1093/oxfordjournals.molbev.a040752

Public

Estimation of the number of nucleotide substitutions when there are strong transition-transversion and G+C-content biases.

Published in Molecular Biology and Evolution • Jul 1, 1992

Authors:

Koichiro Tamura

Abstract

A simple mathematical method is developed to estimate the number of nucleotide substitutions per site between two DNA sequences, by extending Kimura's (1980) two-parameter method to the case where a G+C-content bias exists. This method will be useful when there are strong transition-transversion and...

Subject

Transversion

Biology

Transition (genetics)

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