High-dose intravenous melphalan: a review.

BL, Samuels; JD, Bitran

doi:10.1200/jco.1995.13.7.1786

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High-dose intravenous melphalan: a review.

Shared by NobleBlocks on Jul 1, 1995 • 12:00 AM UTC

Authors:

Samuels BL

Bitran JD

Abstract

Purpose To review the clinical pharmacology and clinical trials that have used intravenous (IV) high-dose melphalan (HDM).Methods We reviewed the mechanism of action, clinical pharmacology, and clinical studies of HDM with and without autologous bone marrow support (ABMT) or peripheral-blood progeni...

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