Characterization of autoantibodies in pemphigus using antigen-specific enzyme-linked immunosorbent assays with baculovirus-expressed recombinant desmogleins

Ishii, Ken; Amagai, Masayuki; P. Hall, Russell; Hashimoto, Takashi; Takayanagi, Atsushi; Gamou, Shinobu; Shimizu, Nobutaka; Níshikaẃa, T.

doi:10.4049/jimmunol.159.4.2010

Public

Characterization of autoantibodies in pemphigus using antigen-specific enzyme-linked immunosorbent assays with baculovirus-expressed recombinant desmogleins

Published in The Journal of Immunology • Aug 1, 1997

Authors:

Ken Ishii

Masayuki Amagai

Russell P. Hall

Abstract

Pemphigus vulgaris (PV) and pemphigus foliaceus (PF) are autoimmune skin diseases caused by autoantibodies against desmoglein (Dsg) 3 and Dsg1, respectively. Routine immunofluorescence testing of skin and serum from patients cannot distinguish between these two severe diseases since both have IgG Ab...

Subject

Pemphigus foliaceus

Desmoglein

Pemphigus vulgaris

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