NK Cell Maturation and Peripheral Homeostasis Is Associated with KLRG1 Up-Regulation

D. Huntington, Nicholas; Tabarias, Hy; A. Fairfax, Kirsten; Brady, Jason; Hayakawa, Yoshihiro; A. Degli‐Esposti, Mariapia; J. Smyth, Mark; M. Tarlinton, David; L. Nutt, Stephen

doi:10.4049/jimmunol.178.8.4764

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NK Cell Maturation and Peripheral Homeostasis Is Associated with KLRG1 Up-Regulation

Published in The Journal of Immunology • Apr 1, 2007

Authors:

Nicholas D. Huntington

Hy Tabarias

Kirsten A. Fairfax

Abstract

NK cells are important for the clearance of tumors, parasites, and virus-infected cells. Thus, factors that control NK cell numbers and function are critical for the innate immune response. A subset of NK cells express the inhibitory killer cell lectin-like receptor G1 (KLRG1). In this study, we ide...

Subject

Interleukin 21

Interleukin 12

Janus kinase 3

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