Association of Plasma Clusterin Concentration With Severity, Pathology, and Progression in Alzheimer Disease

Thambisetty, Madhav; Simmons, Andrew; Velayudhan, Latha; Hye, Abdul; Campbell, James; Zhang, Yi; Wahlund, Lars‐Olof; Westman, Eric; Kinsey, Anna; Güntert, Andreas; Proitsi, Petroula; Powell, John; Čaušević, Mirsada; Killick, Richard; Lunnon, Katie; Lynham, Steven; Broadstock, Martin; Choudhry, Fahd; Howlett, David; J. Williams, Robert; I. Sharp, Sally; Mitchelmore, Cathy; Tunnard, Catherine; Leung, Rufina; Foy, Catherine; P. O’Brien, Darragh; Breen, Gerome; J. Furney, Simon; Ward, Malcolm; Kłoszewska, Iwona; Mecocci, Patrizia; Soininen, Hilkka; Tsolaki, Magda; Vellas, Bruno; Hodges, Angela; Murphy, Declan; Parkins, Sue; Richardson, Jill; M. Resnick, Susan; Ferrucci, Luigi; F. Wong, Dean; Zhou, Yun; Muehlboeck, Sebastian; C. Evans, Alan; T. Francis, Paul; Spenger, Christian; Lovestone, Simon

doi:10.1001/archgenpsychiatry.2010.78

Public

Association of Plasma Clusterin Concentration With Severity, Pathology, and Progression in Alzheimer Disease

Published in Archives of General Psychiatry • Jul 1, 2010

Authors:

Madhav Thambisetty

Andrew Simmons

Latha Velayudhan

Abstract

CONTEXT: Blood-based analytes may be indicators of pathological processes in Alzheimer disease (AD). OBJECTIVE: To identify plasma proteins associated with AD pathology using a combined proteomic and neuroimaging approach. DESIGN: Discovery-phase proteomics to identify plasma proteins associated wit...

Subject

Clusterin

Entorhinal cortex

Alzheimer's disease

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!