Resting Microglia Directly Monitor the Functional State of Synapses<i>In Vivo</i>and Determine the Fate of Ischemic Terminals

Wake, Hiroaki; J. Moorhouse, Andrew; Jinno, Shozo; Kohsaka, Shinichi; Nabekura, Junichi

doi:10.1523/jneurosci.4363-08.2009

Public

Resting Microglia Directly Monitor the Functional State of SynapsesIn Vivoand Determine the Fate of Ischemic Terminals

Published in Journal of Neuroscience • Apr 1, 2009

Authors:

Hiroaki Wake

Andrew J. Moorhouse

Shozo Jinno

Abstract

Recent studies have identified the important contribution of glial cells to the plasticity of neuronal circuits. Resting microglia, the primary immune effector cells in the brain, dynamically extend and retract their processes as if actively surveying the microenvironment. However, just what is bein...

Subject

Microglia

Neuroscience

Biological neural network

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