(-)-Epigallocatechin-3-gallate is a new inhibitor of hepatitis C virus entry.

N, Calland; A, Albecka; S, Belouzard; C, Wychowski; G, Duverlie; V, Descamps; D, Hober; J, Dubuisson; Y, Rouillé; K, Séron

doi:10.1002/hep.24803

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(-)-Epigallocatechin-3-gallate is a new inhibitor of hepatitis C virus entry.

Shared by NobleBlocks on Mar 1, 2012 • 12:00 AM UTC

Authors:

Calland N

Albecka A

Belouzard S

Abstract

Unlabelled Here, we identify (-)-epigallocatechin-3-gallate (EGCG) as a new inhibitor of hepatitis C virus (HCV) entry. EGCG is a flavonoid present in green tea extract belonging to the subclass of catechins, which has many properties. Particularly, EGCG possesses antiviral activity and impairs cell...

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