Dissecting the Maturation Steps of the Lasso Peptide Microcin J25 in vitro

Abstract Microcin J25 is the archetype of a growing class of bacterial ribosomal peptides possessing a knotted topology (lasso peptides). It consists of an eight‐residue macrolactam ring through which the C‐terminal tail is threaded. It is biosynthesized as a precursor that is processed by two matur... View More