The <i>wciN</i> Gene Encodes an α-1,3-Galactosyltransferase Involved in the Biosynthesis of the Capsule Repeating Unit of <i>Streptococcus pneumoniae</i> Serotype 6B

Han, Weiqing; Cai, Li; Wu, Baolin; Li, Lei; Xiao, Zhongying; Cheng, Jiansong; George Wang, Peng

doi:10.1021/bi300640b

Public

The wciN Gene Encodes an α-1,3-Galactosyltransferase Involved in the Biosynthesis of the Capsule Repeating Unit of Streptococcus pneumoniae Serotype 6B

Published in Biochemistry • Jun 28, 2012

Authors:

Weiqing Han

Li Cai

Baolin Wu

Abstract

Almost all Streptococcus pneumoniae (pneumococcus) capsule serotypes employ the Wzy-dependent pathway for their capsular polysaccharide (CPS) biosynthesis. The assembly of the CPS repeating unit (RU) is the first committed step in this pathway. The wciN gene was predicted to encode a galactosyltrans...

Subject

Galactosyltransferase

Biosynthesis

Glycosyltransferase

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!