Long-Term Entecavir Therapy Results in the Reversal of Fibrosis/Cirrhosis and Continued Histological Improvement in Patients with Chronic Hepatitis B†,‡

Chang, Ting‐Tsung; Liaw, Yun‐Fan; Wu, Shun-Sheng; R. Schiff, Eugene; Han, Kwang‐Hyub; Lai, Ching‐Lung; Safadi, Rifaat; S. Lee, Samuel; Halota, Waldemar; Goodman, Zachary; Chi, Yun-Chan; Zhang, Hui; Hindes, R.; H. Iloeje, Uchenna; P. Beebe, S.; Kreter, Bruce

doi:10.1002/hep.23785

Public

Long-Term Entecavir Therapy Results in the Reversal of Fibrosis/Cirrhosis and Continued Histological Improvement in Patients with Chronic Hepatitis B†,‡

Published in Hepatology • Jun 2, 2010

Authors:

Ting‐Tsung Chang

Yun‐Fan Liaw

Shun-Sheng Wu

Abstract

UNLABELLED: One year of treatment with entecavir (0.5 mg daily) in nucleoside-naive patients with hepatitis B e antigen (HBeAg)-positive or HBeAg-negative chronic hepatitis B (CHB) resulted in significantly improved liver histology and virological and biochemical endpoints in comparison with lamivud...

Subject

Entecavir

Medicine

Gastroenterology

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