HLA Association with Hematopoietic Stem Cell Transplantation Outcome: The Number of Mismatches at HLA-A, -B, -C, -DRB1, or -DQB1 Is Strongly Associated with Overall Survival

Loiseau, Pascale; Busson, Marc; Balère, Marie-Lorraine; Dormoy, Anne; Bignon, Jean‐Denis; Gagne, Katia; Gebuhrer, L.; Dubois, Valérie; Jollet, Isabelle; Bois, M.; Perrier, Pascale; Masson, Dominique; Moine, Agnès; Absi, Léna; Reviron, D; Lepage, Virginia; Tamouza, Ryad; Toubert, Antoine; Marry, Évelyne; Chir, Zina; Jouet, Jean‐Pierre; Blaise, Didier; Charron, Dominique; Raffoux, C

doi:10.1016/j.bbmt.2007.04.010

Public

HLA Association with Hematopoietic Stem Cell Transplantation Outcome: The Number of Mismatches at HLA-A, -B, -C, -DRB1, or -DQB1 Is Strongly Associated with Overall Survival

Published in Biology of Blood and Marrow Transplantation • Jul 19, 2007

Authors:

Pascale Loiseau

Marc Busson

Marie-Lorraine Balère

Abstract

HLA matching between the donor and recipient improves the success of unrelated hematopoietic stem cell transplantation (HSCT). Because many patients in need of an unrelated transplant have only donors with mismatch, information is needed to evaluate the limits of HLA mismatching. We examined the ass...

Subject

Medicine

Hazard ratio

Human leukocyte antigen

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