Analysis of Gene Expression in Parkinson's Disease: Possible Involvement of Neurotrophic Support and Axon Guidance in Dopaminergic Cell Death

Bossers, Koen; F. Meerhoff, Gideon; Balesar, Rawien; W. van Dongen, Jeroen; G. Kruse, Chris; F. Swaab, Dick; Verhaagen, Joost

doi:10.1111/j.1750-3639.2008.00171.x

Public

Analysis of Gene Expression in Parkinson's Disease: Possible Involvement of Neurotrophic Support and Axon Guidance in Dopaminergic Cell Death

Published in Brain Pathology • May 7, 2008

Authors:

Koen Bossers

Gideon F. Meerhoff

Rawien Balesar

Abstract

Parkinson's disease (PD) is a neurodegenerative disorder characterized by the progressive loss of dopaminergic neurons in the substantia nigra. We have studied alterations in gene expression in the substantia nigra, the caudate nucleus and putamen of four PD patients and four matched controls using ...

Subject

Substantia nigra

Dopaminergic

Putamen

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