Liver Injury in Acute Fatty Liver of Pregnancy: Possible Link to Placental Mitochondrial Dysfunction and Oxidative Stress

Kumar Natarajan, Sathish; R. Thangaraj, Kavitha; E. Eapen, C.; Ramachandran, Anup; Mukhopadhya, Ashis; Mathai, Mathews; Seshadri, Lakshmi; Vinod Peedikayil, Abraham; Ramakrishna, Banumathi; A. Balasubramanian, Kunnissery

doi:10.1002/hep.23245

Public

Liver Injury in Acute Fatty Liver of Pregnancy: Possible Link to Placental Mitochondrial Dysfunction and Oxidative Stress

Published in Hepatology • Dec 23, 2009

Authors:

Sathish Kumar Natarajan

Kavitha R. Thangaraj

C. E. Eapen

Abstract

UNLABELLED: Acute fatty liver of pregnancy (AFLP) is a rare disorder which is fatal if not recognized and treated early. Delivery of the feto-placental unit results in dramatic improvement in maternal liver function, suggesting a role for the placenta. However, the mechanisms by which defects in the...

Subject

Arachidonic acid

Oxidative stress

Mitochondrion

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!