Superior prevention of acute rejection by tacrolimus vs. cyclosporine in heart transplant recipients--a large European trial.

M, Grimm; M, Rinaldi; NA, Yonan; G, Arpesella; Del Prado JM, Arizón; LA, Pulpón; JP, Villemot; M, Frigerio; Lambert JL, Rodriguez; MG, Crespo-Leiro; L, Almenar; D, Duveau; A, Ordonez-Fernandez; J, Gandjbakhch; M, Maccherini; G, Laufer

doi:10.1111/j.1600-6143.2006.01300.x

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Superior prevention of acute rejection by tacrolimus vs. cyclosporine in heart transplant recipients--a large European trial.

Shared by NobleBlocks on Jun 1, 2006 • 12:00 AM UTC

Authors:

Grimm M

Rinaldi M

Yonan NA

Abstract

We compared efficacy and safety of tacrolimus (Tac)-based vs. cyclosporine (CyA) microemulsion-based immunosuppression in combination with azathioprine (Aza) and corticosteroids in heart transplant recipients. During antibody induction, patients were randomized (1:1) to oral treatment with Tac or Cy...

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