Two tyrosinase nonapeptides recognized on HLA‐A2 melanomas by autologous cytolytic T lymphocytes

Wölfel, Thomas; Van Pel, Aline; Brichard, Vincent; Schneider, Jörg; Seliger, Barbara; Meyer zum Büschenfelde, Karl‐Hermann; Boon, Thierry

doi:10.1002/eji.1830240340

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Two tyrosinase nonapeptides recognized on HLA‐A2 melanomas by autologous cytolytic T lymphocytes

Published in European Journal of Immunology • Mar 1, 1994

Authors:

Thomas Wölfel

Aline Van Pel

Vincent Brichard

Abstract

A number of cytolytic T lymphocyte (CTL) clones derived from several melanoma patients have been found to recognize a majority of melanomas from HLA-A2 patients. We have reported previously that two such CTL clones recognize a product of the tyrosinase gene that is presented by HLA-A2. Here we show ...

Subject

Biology

Cytolysis

Tyrosinase

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