Immunocytochemistry of cGMP in the Cerebellum of the Immature, Adult, and Aged Rat: the Involvement of Nitric Oxide. A Micropharmacological Study

de Vente, Jan; G. J. M. Bol, John; S. Berkelmans, H.; Schipper, J.; Steinbusch, Harry

doi:10.1111/j.1460-9568.1990.tb00396.x

Public

Immunocytochemistry of cGMP in the Cerebellum of the Immature, Adult, and Aged Rat: the Involvement of Nitric Oxide. A Micropharmacological Study

Published in European Journal of Neuroscience • Oct 1, 1990

Authors:

Jan de Vente

John G. J. M. Bol

H. S. Berkelmans

Abstract

In this study we describe the localization of formaldehyde-fixed cGMP-immunoreactivity (cGMP-IR) in rat cerebellar tissue slices incubated in vitro. In the absence of phosphodiesterase inhibition, cGMP-immunofluorescence was of low intensity in tissue slices prepared from immature cerebella. Additio...

Subject

Sodium nitroprusside

Cerebellum

Nitric oxide

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