TRANSPLANTATION OF HEPATOCYTES IN NONHUMAN PRIMATES: A PRECLINICAL MODEL FOR THE TREATMENT OF HEPATIC METABOLIC DISEASES1

Vons, C.; Loux, Nathalie; Simon, L; Mahieu‐Caputo, D.; Dagher, Ibrahim; Andréoletti, Marion; Borgnon, Joséphine; Di Rico, Virginie; Bargy, F.; Capron, Frédérique; Weber, Anne; Franco, A

doi:10.1097/00007890-200109150-00012

Public

TRANSPLANTATION OF HEPATOCYTES IN NONHUMAN PRIMATES: A PRECLINICAL MODEL FOR THE TREATMENT OF HEPATIC METABOLIC DISEASES1

Published in Transplantation • Sep 1, 2001

Authors:

C. Vons

Nathalie Loux

L Simon

Abstract

BACKGROUND: The transplantation of isolated hepatocytes in large animals, including nonhuman primates, must be evaluated before clinical trials are performed. However, in the absence of large transgenic animals and large-animal (as opposed to small-animal) models of genetic deficiencies, it is diffi...

Subject

Transplantation

Liver transplantation

Biology

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