P53-regulated long non-coding RNA TUG1 affects cell proliferation in human non-small cell lung cancer, partly through epigenetically regulating HOXB7 expression

Zhang, E-b; Yin, D-d; Sun, Mingjun; Kong, Rong; Liu, X-h; You, L-h; Han, L; Xia, Rui; Wang, K-m; Yang, J-s; De, Wei; Shu, Y-q; Wang, Z-x

doi:10.1038/cddis.2014.201

Public

P53-regulated long non-coding RNA TUG1 affects cell proliferation in human non-small cell lung cancer, partly through epigenetically regulating HOXB7 expression

Published in Cell Death and Disease • May 22, 2014

Authors:

E-b Zhang

D-d Yin

Mingjun Sun

Abstract

Recently, a novel class of transcripts, long non-coding RNAs (lncRNAs), is being identified at a rapid pace. These RNAs have critical roles in diverse biological processes, including tumorigenesis. Here we report that taurine-upregulated gene 1 (TUG1), a 7.1-kb lncRNA, recruiting and binding to poly...

Subject

Biology

EZH2

Gene knockdown

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!