Derivation of completely cell culture-derived mice from early-passage embryonic stem cells.

Nagy, András; Rossant, Janet; Nagy, Roland; Abramow-Newerly, W; Roder, John

doi:10.1073/pnas.90.18.8424

Public

Derivation of completely cell culture-derived mice from early-passage embryonic stem cells.

Published in Proceedings of the National Academy of Sciences • Sep 15, 1993

Authors:

András Nagy

Janet Rossant

Roland Nagy

Abstract

Several newly generated mouse embryonic stem (ES) cell lines were tested for their ability to produce completely ES cell-derived mice at early passage numbers by ES cell tetraploid embryo aggregation. One line, designated R1, produced live offspring which were completely ES cell-derived as judged by...

Subject

Embryonic stem cell

Biology

Cell culture

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