Ethyl Ferulate, a Lipophilic Polyphenol, Induces HO-1 and Protects Rat Neurons Against Oxidative Stress

Scapagnini, Giovanni; Allan Butterfield, D.; Colombrita, Claudia; Sultana, Rukhsana; Pascale, Alessia; Calabrese, Vittorio

doi:10.1089/ars.2004.6.811

Public

Ethyl Ferulate, a Lipophilic Polyphenol, Induces HO-1 and Protects Rat Neurons Against Oxidative Stress

Published in Antioxidants and Redox Signaling • Oct 1, 2004

Authors:

Giovanni Scapagnini

D. Allan Butterfield

Claudia Colombrita

Abstract

In the CNS, the heme oxygenase (HO) system has been reported to be active and to operate as a fundamental defensive mechanism for neurons exposed to an oxidant challenge. We have recently shown that both curcumin and caffeic acid phenethyl ester, two phenolic natural compounds, potently induce HO-1 ...

Subject

Resveratrol

Oxidative stress

Chemistry

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