A Phase IIIb, randomized, double-blind, placebo-controlled, multicenter study evaluating the safety and efficacy of dexmedetomidine for sedation during awake fiberoptic intubation.

SD, Bergese; KA, Candiotti; PM, Bokesch; A, Zura; W, Wisemandle; AY, Bekker

doi:10.1097/mjt.0b013e3181d69072

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A Phase IIIb, randomized, double-blind, placebo-controlled, multicenter study evaluating the safety and efficacy of dexmedetomidine for sedation during awake fiberoptic intubation.

Shared by NobleBlocks on Nov 1, 2010 • 12:00 AM UTC

Authors:

Bergese SD

Candiotti KA

Bokesch PM

Abstract

GABA-mediated sedatives have respiratory depressant properties that may be detrimental in patients with difficult airways. In this randomized, double-blind, multicenter, Phase IIIb Food and Drug Administration study, safety and efficacy of dexmedetomidine compared with placebo were evaluated as the ...

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