A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1α regulates the <i>VEGF</i> expression and is potentially involved in lung and vascular development

Ema, Masatsugu; Taya, Shin-ichiro; Yokotani, Noboru; Sogawa, Kazuhiro; Matsuda, Youichi; Fujii‐Kuriyama, Yoshiaki

doi:10.1073/pnas.94.9.4273

Public

A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1α regulates the VEGF expression and is potentially involved in lung and vascular development

Published in Proceedings of the National Academy of Sciences • Apr 29, 1997

Authors:

Masatsugu Ema

Shin-ichiro Taya

Noboru Yokotani

Abstract

We have isolated and characterized a cDNA for a novel Per-Arnt/AhR-Sim basic helix-loop-helix (bHLH-PAS) factor that interacts with the Ah receptor nuclear translocator (Arnt), and its predicted amino acid sequence exhibits significant similarity to the hypoxia-inducible factor 1alpha (HIF1alpha) an...

Subject

Biology

Aryl hydrocarbon receptor nuclear translocator

Molecular biology

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!