Activation of Oxidative Stress by Acute Glucose Fluctuations Compared With Sustained Chronic Hyperglycemia in Patients With Type 2 Diabetes

Monnier, Louis; Mas, Emilie; Ginet, Christine; Michel, Françoise; Villon, Laetitia; Cristol, Jean‐Paul; Colette, C

doi:10.1001/jama.295.14.1681

Public

Activation of Oxidative Stress by Acute Glucose Fluctuations Compared With Sustained Chronic Hyperglycemia in Patients With Type 2 Diabetes

Published in JAMA • Apr 11, 2006

Authors:

Louis Monnier

Emilie Mas

Christine Ginet

Abstract

CONTEXT: Glycemic disorders, one of the main risk factors for cardiovascular disease, are associated with activation of oxidative stress. OBJECTIVE: To assess the respective contributions of sustained chronic hyperglycemia and of acute glucose fluctuations to oxidative stress in type 2 diabetes. DES...

Subject

Medicine

Postprandial

Internal medicine

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